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SuperFifty Prime protects plants from Oxidative Stress

BioAtlantis stress mitigation technology primes plants against drought, cold, heat and salinity

Scientists have found that Super Fifty Prime alleviates oxidative stress damage in plants.

The result of research by BioAtlantis was recently published in the International Journal of Molecular Sciences.


Drought, heat, cold and waterlogging are collectively termed by scientists as abiotic stresses. All plants can handle a certain level of abiotic stress. In extreme cases, they cannot cope and respond by producing high levels of harmful compounds referred to as oxidative stress which causes damage to proteins and DNA. Severe oxidative stress can result in crop failure.


The study found that SuperFifty Prime inhibits oxidative stress through “molecular priming”. Using cutting-edge molecular profiling, SuperFifty Prime was shown to confer tolerance to oxidative stress by modulating a range of biological processes in treated plants, including specific genes that initiate cellular and physiological changes.


To prime crops, BioAtlantis recommends that SuperFifty Prime be applied to crops as a foliar spray 3 to 5 days prior to a forecasted extreme weather event, thereby priming and protecting the plant from oxidative stress for 7 to 10 days thereafter.


All plants are challenged with an abiotic stress inducer that increases levels of ROS, leading to cell death. The crops on the right have been primed with SuperFifty Prime. The absence of necrotic lesions indicates that SuperFifty Prime provides full protection against oxidative stress.


Increased Crop Yield

SuperFifty Prime technology has broad implications. Even in well-managed agricultural production systems, crops rarely reach their genetic growth potential and typically only reach 70-75% of their maximum. Treatment with SuperFifty Prime under field conditions across five different crops (tomato, rice, onion, pineapple and wheat) increased yield by 14%. This translates to an increased Return On Sustainable Investmentment (ROSI) for the crop grower.


Climate smart technology

The study also highlights the application of SuperFifty Prime technology as a tool to mitigate against the effects of climate change and improve sustainable practices in agriculture. As a natural and sustainable molecular priming technology, the researchers concluded that: “Collectively, our data reveal that treatment of plants with SuperFifty®Prime prior to a stress may be employed as a climate-smart strategy to alleviate oxidative stress-induced damages in crops”.


EU Research Project: “CropStrengthen”

The research was conducted as part of the EU CropStrengthen Horizon 2020 project (GA No 642901), a Marie Skłodowska-Curie Innovative Training Network focused on developing technologies to increase tolerance of crops to abiotic stresses. CropStrengthen was a collaboration between BioAtlantis Ltd., the Max Planck Institute of Molecular Plant Physiology Potsdam-Golm (Germany), University of Potsdam (Germany), the Center of Plant Systems Biology and Biotechnology Plovdiv, CPSBB (Bulgaria) and Enza Zaden (Netherlands).


Full citation:

Omidbakhshfard MA, Sujeeth N, Gupta S, Omranian N, Guinan KJ, Brotman Y, Nikoloski Z, Fernie AR, Mueller-Roeber B, Gechev TS. A biostimulant obtained from the seaweed Ascophyllum nodosum protects Arabidopsis thaliana from severe oxidative stress. International journal of molecular sciences. 2020 Jan;21(2):474. International Journal of Molecular Sciences. 21(2): 474.